succinate dehydrogenase การใช้

• Further research is required to determine which elimination mechanism succinate undergoes in Succinate Dehydrogenase.
• Others may have mutations in certain subunits of succinate dehydrogenase, a mitochondrial enzyme.
• It is an inhibitor of succinate dehydrogenase.
• Succinate dehydrogenase is an important enzyme in both the citric acid cycle and the electron transport chain.
• This conversion is catalysed by the enzyme succinate dehydrogenase ( or complex II of the mitochondrial ETC ).
• The activity of succinate dehydrogenase is readily observed by the naked eye as the solution turns from colourless to rusty red.
• This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex.
• More recently, it was discovered that certain multiprotein complexes containing succinate dehydrogenase can provide activity similar to that of K ATP channels.
• Binding of NrrF results in down regulation of the sdhCDAB mRNA transcript results in a Fur-dependent positive regulation of succinate dehydrogenase.
• RIP140 suppresses the expression of mitochondrial proteins succinate dehydrogenase complex b and CoxVb and acts as a negative regulator of glucose uptake in mice.
• Under iron limitation, the PrrF RNAs are expressed and act to negatively regulate several genes encoding iron-containing proteins, including SodB and succinate dehydrogenase.
• The glyoxylate cycle utilizes five of the eight enzymes associated with the tricarboxylic acid cycle : citrate synthase, aconitase, succinate dehydrogenase, fumarase, and malate dehydrogenase.
• The old trained men have succinate dehydrogenase activities within their type IIa muscle fibers similar to those in young men and twofold higher than in old normal fit men.
• The SDHD protein is one of the two transmembrane subunits of the four-subunit succinate dehydrogenase ( Complex II ) protein complex that resides in the inner mitochondrial membrane.
• The SDHC protein is one of the two transmembrane subunits of the four-subunit succinate dehydrogenase ( Complex II ) protein complex that resides in the inner mitochondrial membrane.
• The molecular grouping to which it belongs is a pyrazole-4-carboxylic acid amide; its method of action is as a succinate dehydrogenase inhibitor ( SDI ).
• "' Succinate dehydrogenase complex, subunit A, flavoprotein variant "'is a protein that in humans is encoded by the " SDHA " gene.
• Another disease associated with aconitase is Friedreich's ataxia ( FRDA ), which is caused when the Fe-S proteins in aconitase and succinate dehydrogenase have decreased activity.
• Glyoxylate is subsequently combined with acetyl-CoA to produce malate, catalyzed by MS . Malate is also formed in parallel from succinate by the action of succinate dehydrogenase and fumarase.
• A colleague from Cambridge, Tom Singer, had accepted a position at the Henry Ford Hospital in Detroit and recruited Massey to work with him to investigate the enzyme succinate dehydrogenase.